Protein Details: Aquaporin NIP2-2

Protein ID

ICDB_Pro_1072

Protein Name

Aquaporin NIP2-2

Gene Name

NIP2-2; LSI6; Os06g0228200; LOC_Os06g12310; OsJ_019836; P0425F05.28-1

Organism

Oryza sativa subsp. japonica (Rice)

Length

298 amino acids

AlphaFoldDB

AF-Q67WJ8-F1-model_v4.pdb

Function

Silicon transporter involved in the distribution of silicon in shoots. Is responsible for the transport of silicon from the xylem to the leaf tissues. Silicon is beneficial to plant growth and helps plants to overcome abiotic and biotic stresses by preventing lodging (falling over) and increasing resistance to pests and diseases; as well as other stresses . In the nodes; involved with LSI2 and LSI3 in silicon intervascular transfer; which is required for the preferential distribution of silicon; such as hyperaccumulation of silicon in the husk .

Sequence

MASTTAPSRTNSRVNYSNEIHDLSTVQSVSAVPSVYYPEKSFADIFPPNLLKKVISEVVATFLLVFVTCGAASIYGEDMKRISQLGQSVVGGLIVTVMIYATGHISGAHMNPAVTLSFAFFRHFPWIQVPFYWAAQFTGAMCAAFVLRAVLYPIEVLGTTTPTGPHWHALVIEIVVTFNMMFVTCAVATDSRAVGELAGLAVGSAVCITSIFAGPVSGGSMNPARTLAPAVASNVYTGLWIYFLGPVVGTLSGAWVYTYIRFEEAPAAAGGAAPQKLSSFKLRRLQSQSMAADEFDNV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed at low levels in roots and leaves. Expressed in roots; leaf sheaths and leaf blades. In roots; it localizes in the plasma membrane of all cells of the young region and is more abundant on the distal side than the proximal side (at protein level). In roots; it localizes in the plasma membrane of all cells of the young region and is more abundant on the distal side than the proximal side (at protein level). In roots; it localizes in the plasma membrane of all cells of the young region and is more abundant on the distal side than the proximal side (at protein level). Expressed only in the xylem parenchyma cells adjacent to vessels in both leaf sheaths and leaf blades (at protein level). Is more abundant on the side facing the vessel (at protein level).

DOI ID

10.1105/tpc.108.059311; 10.1038/nature03895; 10.1093/nar/gkm978; 10.1186/1939-8433-6-4; 10.1371/journal.pbio.0030038; 10.1126/science.1081288; 10.1093/pcp/pci172; 10.1073/pnas.1508987112

RefSeq

XP_015644134.1

Feature